canine down syndrome

Can Dog Have Canine Down Syndrome?

 

Anybody who has spent plenty of time around dogs knows the compatibility between the canine and individual species. To paraphrase Forrest Gump, we “goes together like peas and carrots.” Why is the human-dog venture so ideal is our distinctive mixture of similarities and differences.

But sometimes our similarities have a dark side–such as the ailments that affect both people and dogs. These include certain forms of cancer, diabetes, epilepsy, and congestive heart failure to mention only a couple. Down syndrome is a common chromosomal abnormality in individuals. The question that naturally follows is “Can puppies have allergies?”

What is Canine Down Syndrome?

 

To answer this query, we first need to know what Down syndrome is. The National Down Syndrome Society provides a Fantastic explanation:

In each cell in the body, there’s a nucleus, in which genetic material is stored in enzymes. Genes carry the codes accountable for all of our inherited traits and are grouped together rod-like structures known as chromosomes. Normally, the nucleus of every cell includes 23 pairs of chromosomes, half of which are inherited from each parent. Down syndrome occurs when an individual includes a partial or full additional copy of chromosome 21.

What Are the Signs of Canine Down Syndrome?

The existence of the additional genetic material may have a vast array of effects. Individuals with Down syndrome have a certain degree of intellectual impairment, but that may vary widely between people. Based the US Centers for Disease Control and Prevention (CDC), a number of the common physical characteristics of Down syndrome include:

– A flattened face, particularly the bridge of the nose
– Almond-shaped eyes that booted up
– A Brief neck
– Little ears
– A tongue which will stand out from this mouth
– Tiny white spots on the iris (colored part) of this eye
– Little hands and toes
– One line Throughout the palm of their hands (palmar crease)
– Little pinky fingers that occasionally bend toward the thumb
– Poor muscle tone or loose joints
– Shorter in height as kids and adults

Individuals with Down syndrome may also have a assortment of health care issues. The CDC reports these as the most typical:

– Hearing loss (around 75 percent of individuals with Down syndrome could be influenced)
– Obstructive sleep apnea, which is a condition in which the individual’s breathing stops ceases while asleep (involving 50 -75 percent)
– borne illnesses (between 50 -70 percent)
– Eye ailments (up to 60 percent), such as cataracts and eye problems requiring eyeglasses
– Heart defects present at birth (50 percent)

May Cells Have Canine Down Syndrome?

Deciding whether dogs may have Down syndrome is dependent upon how you consider the question. The CDC estimates that roughly 1 in every 700 babies born in the USA has Down syndrome. The exact same certainly can not be said about puppies. If Down syndrome does occur in puppies, it’s a much rarer event.

Genetically, dogs and individuals have lots of similarities but significant differences obviously do exist. As an instance, individuals have 23 sets of chromosomes while puppies have 39. Consequently, duplication of part or all of chromosome 21 could have different consequences in both species. Interestingly however, scientists have been using genetically engineered mice as animal models in Down syndrome study. These mice carry an excess part of their chromosome 16, which includes genes similar to those contained on human chromosome 21. The outcome is a mouse that has some characteristics similar to human Down syndrome. Remember, however, that these aren’t naturally occurring mice; they’ve been genetically engineered.

Even enlarging the definition of puppy Down syndrome to incorporate any hereditary duplication that leads to clinical abnormalities like those found in individuals with Down syndrome, the illness simply hasn’t yet been described in dogs. Three explanations are possible:

– These kinds of chromosomal abnormalities normally contribute to premature death in puppies.
– The genetic testing required to identify dogs with Down syndrome only is not done.
– The illness truly does not exist.

Conditions that Appear Like Canine Down Syndrome in Dogs

On the flip side, hereditary or congenital conditions are regularly diagnosed with dogs which possess some clinical similarities with Down syndrome. Congenital hypothyroidism is an excellent example. It’s Brought on by low or absent levels of thyroid gland in dawn and early in life, which contributes to some mix of these:

– Slow expansion eventually Leading to small stature
– Broad mind
– Large, protruding tongue
– Brief limbs
– Unusual gait
– Poor muscle tone
– Emotional dullness
– Delayed opening of their eyes and eyes
– Delayed tooth eruption

Other ailments that could be mistaken with Down syndrome in dogs consist of pituitary dwarfism, congenital hydrocephalus, growth hormone deficiency, and portosystemic shunt.

If you feel that your dog might have a condition such as Down syndrome, speak with your vet. They can suggest an proper diagnostic strategy and make treatment recommendations after a diagnosis is set up.




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